Regina Hofmann-Lehmann is professor for Laboratory Medicine at the Faculty of Veterinary Medicine (Vetsuisse Faculty), University of Zurich. She was studying retrovirus infections at the Dana-Farber Cancer Institute and Harvard Medical School in Boston from 1998 to 2001. In 2004 she received as the only veterinarian so far, a professorship of the Swiss National Science Foundation (SNSF). Since 2010 she serves as President of the Swiss Association of Veterinary Laboratory Diagnosticians.
Her main research interests are in clinical infectiology with a focus on retroviruses, haemoplasmas and infections in domestic and wild felids. She is the author of >260 publications in peer-reviewed journals in this field. Her research has been funded by the SNSF since 1998 and involves collaborations with many research groups and institutions worldwide.
Since 2011 she is Head of the Clinical Laboratory. The multivalent laboratory (www.vetlabor.ch) receives 30’000 samples/year from farm, companion and exotic animal patients of the University Teaching Hospital and from several zoos for hematology, cytology, flow cytometry, clinical chemical and serological and molecular analyses of infectious diseases. The Clinical Laboratory is the only laboratory in Switzerland accredited by the European College of Veterinary Clinical Pathology (ECVCP).
Since 2011 she is also Head of the Center for Clinical Studies (www.zks.uzh.ch), a core facility dedicated to support the laboratory-based clinical research mainly of the clinicians of the Faculty. The center has more than 150 users from 27 research groups.
In 2017 she was elected additionally as Head of the Department of Clinical Diagnostics and Services and with that became Member of the Executive Board of the University Animal Hospital at the University of Zurich.
My list of ten selected publications:
Nentwig A, ML Meli, J Schrack, IM Reichler, B Riond, C Gloor, J Howard, R Hofmann-Lehmann, B Willi. 2018. First report of Cytauxzoon sp. infection in domestic cats in Switzerland: natural and transfusion-transmitted infections. Parasit Vectors 11:292. doi: 10.1186/s13071-018-2728-5. https://www.ncbi.nlm.nih.gov/pubmed/29747680
Novacco M, S Sugiarto, B Willi, J Baumann, AM Spiri, A Oestmann, B Riond, FS Boretti, H Naegeli, R Hofmann-Lehmann. 2018. Consecutive antibiotic treatment with doxycycline and marbofloxacin clears bacteremia in Mycoplasma haemofelis-infected cats. Vet Microbiol 217:112-120. doi: 10.1016/j.vetmic.2018.03.006. Epub 2018 Mar 10. https://www.ncbi.nlm.nih.gov/pubmed/29615243
Meli ML, A Berger, B Willi, AM Spiri, B Riond, R Hofmann-Lehmann. 2018. Molecular detection of feline calicivirus in clinical samples: a study comparing its detection by RT-qPCR directly from swabs and after virus isolation. qPCR directly from swabs and after virus isolation. J Virol Methods 251:54-60. doi: 10.1016/j.jviromet.2017.10.001. Epub 2017 Oct 3. https://www.ncbi.nlm.nih.gov/pubmed/28986291
Willi B, Spiri AM, Melia ML, Samman A, Hoffmann K, Sydler T, Cattoria V, Graf F, Diserens KA, Padrutt I, Nesina S, Berger A, Ruetten M, Riond B, Hosie MJ, Hofmann-Lehmann R. 2016. Molecular characterization and virus neutralization patterns of severe, non-epizootic forms of feline calicivirus infections resembling virulent systemic disease in cats in Switzerland and in Liechtenstein. Vet Microbiol 182:202-12. doi: 10.1016/j.vetmic.2015.10.015. http://www.ncbi.nlm.nih.gov/pubmed/26711049
Nesina S, Helfer-Hungerbuehler K, Riond B, Boretti FS, Willi B, Marina M, Grest P, Hofmann-Lehmann R. 2015. Retroviral DNA—the silent winner: blood transfusion containing latent feline leukemia provirus causes infection and disease in naïve recipient cats. Retrovirology 12:105. doi: 10.1186/s12977-015-0231-z. http://www.ncbi.nlm.nih.gov/pubmed/26689419
Berger A, Willi B, Meli ML, Boretti FS, Hartnack S, Dreyfus A, Lutz H, Hofmann-Lehmann R. 2015. Feline calicivirus and other respiratory pathogens in cats with feline calicivirus-related symptoms and in clinically healthy cats in Switzerland. BMC Vet Res 13;11:282. doi: 10.1186/s12917-015-0595-2. http://www.ncbi.nlm.nih.gov/pubmed/26566897
Helfer-Hungerbuehler AK, AM Spiri, B Riond, P Grest, FS Boretti, Regina Hofmann-Lehmann. 2015. No benefit of therapeutic vaccination in clinically healthy cats persistently infected with feline leukemia virus. Vaccine. 33:1578-85. doi: 10.1016/j.vaccine.2015.02.009. http://www.ncbi.nlm.nih.gov/pubmed/25698488
Baumann J, M Novacco, B Willi, B Riond, ML Meli, FS Boretti, R Hofmann-Lehmann. 2015. Lack of cross-protection against Mycoplasma haemofelisinfection and signs of enhancement in ‘CandidatusMycoplasma turicensis’-recovered cats. Vet Res 46:104. doi: 10.1186/s13567-015-0240-x. http://www.ncbi.nlm.nih.gov/pubmed/26403079
Hofmann-Lehmann R, V Cattori, R Tandon, FS Boretti, ML Meli, B Riond, AC Pepin, B Willi, P Ossent, H Lutz. 2007. Vaccination against the feline leukaemia virus: Outcome and response categories and long-term follow-up. Vaccine 25: 5531-5539. http://www.ncbi.nlm.nih.gov/pubmed/17240486
Willi B, FS Boretti, V Cattori,S Tasker, ML Meli,CE Reusch, H Lutz, R Hofmann-Lehmann. 2005. Identification, molecular characterization and experimental transmission of a new hemoplasma isolate from a cat with hemolytic anemia in Switzerland. J Clin Microbiol 43: 2581-2585. http://www.ncbi.nlm.nih.gov/pubmed/15956367
Corine Boucraut- Baralon
Marian C. Horzinek
Maria Grazia Pennisi