Hofmann w flagRegina Hofmann-Lehmann is professor for Laboratory Medicine and Head of the Clinical Laboratory of the Vetsuisse Faculty, University of Zurich.


The multivalent laboratory receives 30’000 samples/year from patients of the teaching hospital and from zoos mainly for hematological, clinical chemical, immunological and molecular analyses. Since 2011 she is also Head of the Center for Clinical Studies, a core facility dedicated to support the laboratory-based clinical research.


From 1998 to 2001, she was a researcher studying retrovirus infections at the Dana-Farber Cancer Institute and Harvard Medical School in Boston and in 2004 she received as the only veterinarian so far a professorship of the Swiss National Science Foundation.


Since 2010 she serves as President of the Swiss Association of Veterinary Laboratory Diagnosticians.


Her main research interest are in clinical infectiology with a focus on retroviruses, haemoplasmas and infections in domestic and wild felids. She is the author of >200 publications in peer-reviewed journals in this field.



My list of ten selected publications:


    • Willi B, Spiri AM, Melia ML, Samman A, Hoffmann K, Sydler T, Cattoria V, Graf F, Diserens KA,  Padrutt I, Nesina S, Berger A, Ruetten M, Riond B, Hosie MJ, Hofmann-Lehmann R. 2016. Molecular characterization and virus neutralization patterns of severe, non-epizootic forms of feline calicivirus infections resembling virulent systemic disease in cats in Switzerland and in Liechtenstein. Vet Microbiol 182:202-12. doi: 10.1016/j.vetmic.2015.10.015. http://www.ncbi.nlm.nih.gov/pubmed/26711049


      • Nesina S, Helfer-Hungerbuehler K, Riond B, Boretti FS, Willi B, Marina M, Grest P, Hofmann-Lehmann R. 2015. Retroviral DNA—the silent winner: blood transfusion containing latent feline leukemia provirus causes infection and disease in naïve recipient cats. Retrovirology 12:105. doi: 10.1186/s12977-015-0231-z. http://www.ncbi.nlm.nih.gov/pubmed/26689419


        • Willi B, AM Spiri, ML Meli, F Grimm, L Beatrice, B Riond, T Bley, R Jordi, M Dennler, R Hofmann-Lehmann. 2015. Clinical and molecular investigation of a canine distemper outbreak and vector-borne infections in a group of rescue dogs imported from Hungary to c. BMC Vet Res. 2015 Jul 16;11:154. doi: 10.1186/s12917-015-0471-0. http://www.ncbi.nlm.nih.gov/pubmed/26179635


          • Berger A, Willi B, Meli ML, Boretti FS, Hartnack S, Dreyfus A, Lutz H, Hofmann-Lehmann R. 2015. Feline calicivirus and other respiratory pathogens in cats with feline calicivirus-related symptoms and in clinically healthy cats in Switzerland. BMC Vet Res 13;11:282. doi: 10.1186/s12917-015-0595-2. http://www.ncbi.nlm.nih.gov/pubmed/26566897


            • Helfer-Hungerbuehler AK, AM Spiri, B Riond, P Grest, FS Boretti, Regina Hofmann-Lehmann. 2015. No benefit of therapeutic vaccination in clinically healthy cats persistently infected with feline leukemia virus. Vaccine. 33:1578-85. doi: 10.1016/j.vaccine.2015.02.009. http://www.ncbi.nlm.nih.gov/pubmed/25698488


              • Hornok S, Takács N, Kontschán J, György Z, Micsutka A, Iceton S, Flaisz B, Farkas R, Hofmann-Lehmann R. 2015. Diversity of Haemaphysalis-associated piroplasms of ruminants in Central-Eastern Europe, Hungary. Parasit Vectors 8:627. DOI 10.1186/s13071-015-1236-0. http://www.ncbi.nlm.nih.gov/pubmed/26652614


                • Baumann J, M Novacco, B Willi, B Riond, ML Meli, FS Boretti, R Hofmann-Lehmann. 2015. Lack of cross-protection against Mycoplasma haemofelisinfection and signs of enhancement in ‘Candidatus Mycoplasma turicensis’-recovered cats. Vet Res 46:104. doi: 10.1186/s13567-015-0240-x. http://www.ncbi.nlm.nih.gov/pubmed/26403079


                  • Hornok S, D Kováts, T. Csörgő, ML Meli, E Gönczi, N Takács, R Farkas, R Hofmann-Lehmann. 2014. Birds as potential reservoirs of tick-borne pathogens: first evidence of bacteraemia with Rickettsia helvetica. Parasit Vectors 7:128. doi: 10.1186/1756-3305-7-128. http://www.ncbi.nlm.nih.gov/pubmed/24679245


                    • Hofmann-Lehmann R, V Cattori, R Tandon, FS Boretti, ML Meli, B Riond, AC Pepin, B Willi, P Ossent, H Lutz. 2007. Vaccination against the feline leukaemia virus: Outcome and response categories and long-term follow-up. Vaccine 25: 5531-5539. http://www.ncbi.nlm.nih.gov/pubmed/17240486


                    • Willi B, FS Boretti, V Cattori,S Tasker, ML Meli, CE Reusch, H Lutz, R Hofmann-Lehmann. 2005. Identification, molecular characterization and experimental transmission of a new hemoplasma isolate from a cat with hemolytic anemia in Switzerland. J Clin Microbiol 43: 2581-2585. http://www.ncbi.nlm.nih.gov/pubmed/15956367


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