Margaret Hosie

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Margaret Hosie is Professor of Comparative Virology at the MRC-University of Glasgow Centre for Virus Research https://www.gla.ac.uk/researchinstitutes/iii/staff/margarethosie/. A veterinarian, she completed her Ph.D. studies on feline immunodeficiency virus in 1991 and subsequently she has pursued an academic research and teaching career in Glasgow, collaborating with colleagues in Europe, US, Australia and Japan.  She conducts research in infectious disease pathogenesis, diagnostics and vaccine development, with a focus on feline viruses. In 2002 she was awarded Recognised Specialist Status in Pathology (Microbiology) by the Royal College of Veterinary Surgeons, in recognition of her contributions to these fields.

 

Her most significant scientific contributions have included the identification of determinants of virulence amongst feline immunodeficiency virus (FIV) isolates, the development of methods to confirm FIV and feline leukaemia virus infections in diagnostic samples, the identification of vaccine-induced enhancement of FIV infection and elucidation of the mechanism of protection induced by whole inactivated FIV vaccines. She has also identified immunological correlates of feline retroviral infection, discovered the primary and co-receptor molecules for FIV infection, and more recently identified the first case of human-to-cat transmission of SARS-CoV-2 in the UK. Over the years, her research findings have had implications for improving feline welfare as well as having wider, comparative significance.

 

Prof Hosie has served as a member of the Editorial Boards of Virus Genes and BMC Veterinary Research and is currently a member of the UK Veterinary Vaccinology Network and the British Veterinary Association Policy Group. She is the INSPIRE lead for the School of Veterinary Medicine and actively encourages veterinary undergraduates to engage with research activities. She is also a member of the panel that is responsible for updating the AAFP: Feline Retrovirus Management Guidelines. She has been a member of the European Advisory Board for Cat Diseases (ABCD) since 2005 and was elected as President of the newly established Association, ABCD Europe, in 2019.

My list of 10 selected publications:

  • Hu S, Logan N, Puenpa J, Wanlapakorn N, Vongpunsawad S, Poovorawan Y, Willett BJ, Hosie MJ. Evaluation of the effect of maternally derived antibody on response to MMR vaccine in Thai infants. Vaccine. 2022 Mar 1;40(10):1439-1447. doi: 10.1016/j.vaccine.2022.01.049. Epub 2022 Feb 
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  • Frymus T, Belák S, Egberink H, Hofmann-Lehmann R, Marsilio F, Addie DD, Boucraut-Baralon C, Hartmann K, Lloret A, Lutz H, Pennisi MG, Thiry E, Truyen U, Tasker S, Möstl K, Hosie MJ. Influenza Virus Infections in Cats. 2021 Jul 23;13(8):1435. doi: 10.3390/v13081435.PMID: 34452300 
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  • Hosie MJ, Epifano I, Herder V, Orton RJ, Stevenson A, Johnson N, MacDonald E, Dunbar D, McDonald M, Howie F, Tennant B, Herrity D, Da Silva Filipe A, Streicker DG; COVID-19 Genomics UK (COG-UK) consortium, Willett BJ, Murcia PR, Jarrett RF, Robertson DL, Weir W. Detection of SARS-CoV-2 in respiratory samples from cats in the UK associated with human-to-cat transmission. Vet Rec. 2021 Apr;188(8):e247. doi: 10.1002/vetr.247. Epub 2021 Apr 22. PMID: 33890314 
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  • Hosie MJ, Hofmann-Lehmann R, Hartmann K, Egberink H, Truyen U, Addie DD, Belák S, Boucraut-Baralon C, Frymus T, Lloret A, Lutz H, Marsilio F, Pennisi MG, Tasker S, Thiry E, Möstl K. Anthropogenic infection of cats during the 202COVID-19 pandemic. Viruses. 2021 Jan 26;13(2):185. doi: 10.3390/v13020185. PMID: 33530620 
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  • Hosie MJ and Jasim S. The case for adopting a combined comparative medicine and One Health approach to tackle emerging diseases. Research Comment, The Veterinary Record doi: 10.1136/vr.m2686
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  • Gilbert M, Sulikhan N, Uphyrkina O, Goncharuk M, Kerley L, Castro EH, Reeve R, Seimon T, McAloose D, Seryodkin IV, Naidenko SV, Davis CA, Wilkie GS, Vattipally SB, Adamson WE, Hinds C, Thomson EC, Willett BJ, Hosie MJ, Logan N, McDonald M, Ossiboff RJ, Shevtsova EI, Belyakin S, Yurlova AA, Osofsky SA, Miquelle DG, Matthews L, Cleaveland S. Distemper, extinction, and vaccination of the Amur tiger. Proc Natl Acad Sci U S A. 2020 Dec 15;117(50):31954-31962. doi: 10.1073/pnas.2000153117. Epub 2020 Nov 23.PMID: 33229566 
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  • Noad RJ, Simpson K, Fooks AR, Hewson R, Gilbert SC, Stevens MP, Hosie MJ, Prior J, Kinsey AM, Entrican G, Simpson A, Whitty CJM, Carroll MW. UK vaccines network: Mapping priority pathogens of epidemic potential and vaccine pipeline developments. Vaccine. 2019 Oct 8;37(43):6241-6247. doi: 10.1016/j.vaccine.2019.09.009. Epub 2019 Sep 12. PMID: 31522809; PMCID: PMC7127063.
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  • Abdullah N, Kelly JT, Graham SC, Birch J, Gonçalves-Carneiro D, Mitchell T, Thompson RN, Lythgoe KA, Logan N, Hosie MJ, Bavro VN, Willett BJ, Heaton MP, Bailey D. Structure-Guided Identification of a Nonhuman Morbillivirus with Zoonotic Potential. J Virol. 2018 Nov 12;92(23):e01248-18. doi: 10.1128/JVI.01248-18. PMID: 30232185; PMCID: PMC6232486.
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  • Hosie MJ, Techakriengkrai N, Bęczkowski PM, Harris M, Logan N, Willett BJ. The Comparative Value of Feline Virology Research: Can Findings from the Feline Lentiviral Vaccine Be Translated to Humans? Vet Sci. 2017 Jan 28;4(1):7. doi: 10.3390/vetsci4010007. PMID: 29056666; PMCID: PMC5606627.
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  • Logan N, Dundon WG, Diallo A, Baron MD, James Nyarobi M, Cleaveland S, Keyyu J, Fyumagwa R, Hosie MJ, Willett BJ. Enhanced immunosurveillance for animal morbilliviruses using vesicular stomatitis virus (VSV) pseudotypes. Vaccine. 2016 Nov 11;34(47):5736-5743. doi: 10.1016/j.vaccine.2016.10.010. Epub 2016 Oct 11. PMID: 27742221; PMCID: PMC5084683.

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